Pattern of expression of apoptosis and inflammatory genes in humans exposed to arsenic and/or fluoride.

@article{SalgadoBustamante2010PatternOE,
  title={Pattern of expression of apoptosis and inflammatory genes in humans exposed to arsenic and/or fluoride.},
  author={Mariana Salgado-Bustamante and Mar{\'i}a D. Ortiz-P{\'e}rez and Emma S. Calder{\'o}n-Aranda and Lizbeth Estrada-Capetillo and Perla Del Carmen Ni{\~n}o-Moreno and Roberto Gonz{\'a}lez-Amaro and Diana Patricia Portales-P{\'e}rez},
  journal={The Science of the total environment},
  year={2010},
  volume={408 4},
  pages={
          760-7
        }
}
We have assessed whether the combined exposure to arsenic (As) and fluoride (F) exerts a different effect than the exposure to As alone on the pattern of expression of apoptosis and inflammatory genes by immune cells. RNA was extracted from peripheral blood mononuclear cells from twenty individuals exposed or not to As or F or both. Then, cDNA was isolated, and the expression of 180 genes related to apoptosis and inflammation was tested by a cDNA array test. We found significant differences in… CONTINUE READING
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