Pattern of expression of adiponectin receptors in human liver and its relation to nonalcoholic steatohepatitis.

@article{Nannipieri2009PatternOE,
  title={Pattern of expression of adiponectin receptors in human liver and its relation to nonalcoholic steatohepatitis.},
  author={Monica Nannipieri and Federica Cecchetti and Marco Anselmino and Elena Mancini and Gianfranco Marchetti and A. Bonotti and Simona Baldi and Biagio Solito and Monica Giannetti and Aldo Pinchera and Ferruccio Santini and Ele Ferrannini},
  journal={Obesity surgery},
  year={2009},
  volume={19 4},
  pages={467-74}
}
BACKGROUND Adiponectin has antisteatosis-anti-inflammatory properties and its circulating levels are reduced in nonalcoholic steatohepatitis (NASH). METHODS To assess the role of adiponectin in NASH, we measured expression of adiponectin gene (APM1) and receptors (AdipoR1/AdipoR2) in liver and subcutaneous and visceral fat in subjects with biopsy-proven NASH or pure steatosis (PS). In 103 subjects undergoing gastric bypass or elective abdominal surgery (17 with normal liver histology (C), 52… CONTINUE READING
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