Pattern of epithelial cell proliferation in colorectal mucosa of normal subjects and of patients with adenomatous polyps or cancer of the large bowel.

@article{Leon1988PatternOE,
  title={Pattern of epithelial cell proliferation in colorectal mucosa of normal subjects and of patients with adenomatous polyps or cancer of the large bowel.},
  author={Maurizio Ponz de Leon and Luca Roncucci and Pietro Di Donato and Laura Tassi and O Smerieri and M G Amorico and G A Malagoli and D de Maria and A Antonioli and Nabil Jamil Chahin},
  journal={Cancer research},
  year={1988},
  volume={48 14},
  pages={4121-6}
}
Microautoradiography has been largely used to characterize the proliferative activity of colorectal mucosa. We used this technique in a large series of patients with polyps or cancer of the large bowel and in normal controls with the following objectives: (a) to define the normal pattern of cell replication in different tracts of the large bowel; (b) to compare the proliferative activity of colonic crypts in patients with colorectal cancer or polyps with that of controls; (c) to evaluate… CONTINUE READING