Pattern of antioxidant and DNA repair gene expression in normal airway epithelium associated with lung cancer diagnosis.

@article{Blomquist2009PatternOA,
  title={Pattern of antioxidant and DNA repair gene expression in normal airway epithelium associated with lung cancer diagnosis.},
  author={Thomas M. Blomquist and Erin L. Crawford and D N Mullins and Youngsook Yoon and D Hern{\'a}ndez and Sadik A. Khuder and Patricia L Ruppel and Elizabeth Peters and David J Oldfield and Brad Austermiller and John Anders and James C. Willey},
  journal={Cancer research},
  year={2009},
  volume={69 22},
  pages={8629-35}
}
In previous studies, we reported that key antioxidant and DNA repair genes are regulated differently in normal bronchial epithelial cells of lung cancer cases compared with non-lung cancer controls. In an effort to develop a biomarker for lung cancer risk, we evaluated the transcript expressions of 14 antioxidant, DNA repair, and transcription factor genes in normal bronchial epithelial cells (HUGO names CAT, CEBPG, E2F1, ERCC4, ERCC5, GPX1, GPX3, GSTM3, GSTP1, GSTT1, GSTZ1, MGST1, SOD1, and… CONTINUE READING

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