Pattern of alloimmune response in second same donor allografts after induction of tolerance using CTLA4Ig.

Abstract

BACKGROUND The pattern of allograft acceptance in the presence of costimulatory blockade is manifested by the sequential appearance of Th1 cells, followed by Th2 cells. The aim of this study was to examine whether this phenomenon repeats itself after second same donor allotransplantation, hoping to determine whether acceptance in this setting provokes a… (More)

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