Pattern formation by local self-activation and lateral inhibition.

  title={Pattern formation by local self-activation and lateral inhibition.},
  author={Hans Meinhardt and Alfred Gierer},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  volume={22 8},
In 1972, we proposed a theory of biological pattern formation in which concentration maxima of pattern forming substances are generated through local self-enhancement in conjunction with long range inhibition. Since then, much evidence in various developmental systems has confirmed the importance of autocatalytic feedback loops combined with inhibitory… CONTINUE READING