Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors.

  title={Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors.},
  author={Matthew R. Weir and George L. Bakris and David A. Bushinsky and Martha R. Mayo and Dahlia Garza and Yuri Stasiv and Janet Turk Wittes and Heidi Christ-schmidt and Lance Berman and Bertram Pitt},
  journal={The New England journal of medicine},
  volume={372 3},
BACKGROUND Hyperkalemia increases the risk of death and limits the use of inhibitors of the renin-angiotensin-aldosterone system (RAAS) in high-risk patients. We assessed the safety and efficacy of patiromer, a nonabsorbed potassium binder, in a multicenter, prospective trial. METHODS Patients with chronic kidney disease who were receiving RAAS inhibitors and who had serum potassium levels of 5.1 to less than 6.5 mmol per liter received patiromer (at an initial dose of 4.2 g or 8.4 g twice a… 

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