Patients with obsessive-compulsive disorder have increased 5-HT2A receptor binding in the caudate nuclei.

@article{Adams2005PatientsWO,
  title={Patients with obsessive-compulsive disorder have increased 5-HT2A receptor binding in the caudate nuclei.},
  author={K. H. Adams and Elsebeth S Hansen and Lars H. Pinborg and Steen G. Hasselbalch and Claus Svarer and S\oren Holm and Tom Gert Bolwig and Gitte Moos Knudsen},
  journal={The international journal of neuropsychopharmacology},
  year={2005},
  volume={8 3},
  pages={391-401}
}
The pharmacological efficacy of serotonergic-acting drugs suggest that patients with obsessive-compulsive disorder (OCD) may have alterations in their cerebral serotonergic (5-HT) receptor system, and previous neuroimaging studies of OCD patients have shown abnormalities in several fronto-subcortical regions. In this study we investigated cerebral 5-HT(2A… CONTINUE READING