Patients with head and neck cancer cured by radiation therapy: A survey of the dry mouth syndrome in long‐term survivors

@article{Wijers2002PatientsWH,
  title={Patients with head and neck cancer cured by radiation therapy: A survey of the dry mouth syndrome in long‐term survivors},
  author={Oda B. Wijers and Peter C. Levendag and M. Braaksma and Meindert Boonzaaijer and L L Visch and Paul I. M. Schmitz},
  journal={Head \& Neck},
  year={2002},
  volume={24}
}
Xerostomia can have a significant impact on the quality of life of patients treated by radiation therapy (RT) for cancer in the head and neck. The first aim of the study was to evaluate the degree of xerostomia in 39 long‐term survivors treated between 1965–1995 by conventional two‐dimensional radiation therapy and currently without evidence of disease. The second aim was to develop a concise instrument to evaluate the subjective aspects of xerostomia. 
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TLDR
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Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy.
TLDR
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Different populations of head and neck cancer patients from this institution have been analysed concerning aspects of treatment, sequelae, and rehabilitation, and the effect of an early preventive rehabilitation programme on functional losses and quality of life is evaluated.
Radiation-induced xerostomia: pathophysiology, prevention and treatment.
TLDR
A review of published studies describing and reporting xerostomia is presented and advances made in the prevention and treatment of this common toxicity are discussed.
Functional outcomes related to the prevention of radiation‐induced xerostomia: Oral pilocarpine versus submandibular salivary gland transfer
TLDR
This study examined functional outcomes related to 2 saliva‐sparing treatments: (1) oral pilocarpine during radiotherapy; or the submandibular salivary gland transfer (SGT) before radiotherapy.
Radiotherapy-related quality of life in patients with head and neck cancers: a meta-analysis
TLDR
IMRT significantly improves QoL and reduces the severity of xerostomia in patients with head and neck cancer and provides clinicians with guidelines for decisions on the use of IMRT versus conventional RT.
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