• Corpus ID: 19052073

Patients with coeliac disease are increasingly overweight or obese on presentation.

@article{Tucker2012PatientsWC,
  title={Patients with coeliac disease are increasingly overweight or obese on presentation.},
  author={E E Tucker and Kamran Rostami and Sudhakaran Prabhakaran and Daivid Al Dulaimi},
  journal={Journal of gastrointestinal and liver diseases : JGLD},
  year={2012},
  volume={21 1},
  pages={
          11-5
        }
}
BACKGROUND Historically weight loss is a classic symptom of Coeliac Disease (CD). Recent studies suggest CD sufferers are significantly more likely to be obese or underweight at the time of presentation. This study aimed to establish the frequency of obesity in newly diagnosed Coeliac Disease (CD). METHODS Dietetic records of CD patients were reviewed and patient demographics, initial assessment date, and Body Mass Index (BMI) recorded and statistically analysed. RESULTS out of 187 CD… 

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References

SHOWING 1-10 OF 27 REFERENCES

Overweight in Celiac Disease: Prevalence, Clinical Characteristics, and Effect of a Gluten-Free Diet

Few celiac patients are underweight at diagnosis and a large minority is overweight; these are less likely to present with classical features of diarrhea and reduced hemoglobin, and the gluten-free diet as conventionally prescribed needs to be modified accordingly.

Obesity in Pediatric Celiac Disease

Obesity is more common in children with CD than previously recognized and must be considered even in obese children, according to the appropriate clinical setting.

Body Mass Index in Celiac Disease: Beneficial Effect of a Gluten-free Diet

A GFD had a beneficial impact on BMI, underweight patients gained weight and overweight/obese patients lost weight, and the improvement in BMI adds to the impetus to diagnose celiac disease.

Celiac Disease in Normal-weight and Overweight Children: Clinical Features and Growth Outcomes Following a Gluten-free Diet

A GFD may have a beneficial effect upon the BMI of overweight and obese children with celiac disease, and to study their BMI changes following a gluten-free diet (GFD).

Gender and clinical presentation in adult celiac disease.

The clinical presentation of celiac disease is not the same in men and women and the data suggest the need to look for Celiac disease in patients with unexplained hypochromic anemia.

Coeliac disease and body mass index: A study of two Swedish general population-based registers

Underweight individuals are at increased risk of having undiagnosed coeliac disease, however, overweight does not rule out CD.

Atypical presentation is dominant and typical for coeliac disease.

There is a high prevalence of CD antibodies among patients with GI symptoms (3.7%).

A case-control study of presentations in general practice before diagnosis of coeliac disease.

Depression and/or anxiety and diarrhoea and anaemia remained associated with subsequent diagnosis of coeliac disease even when data for the year prior to diagnosis was excluded from the analysis.

Sensitivity of antiendomysium and antigliadin antibodies in untreated celiac disease: disappointing in clinical practice

The experience shows that EMA and AGA have only limited value in screening programs for CD, and although EMA sensitivity in total villous atrophy is excellent, in partial villus atrophy the sensitivity of EMA appears to be disappointing.

Current approaches to diagnosis and treatment of celiac disease: an evolving spectrum.

The current gold standard for the diagnosis of CD remains histologic confirmation of the intestinal damage in serologically positive individuals, and the keystone treatment of CD patients is a lifelong elimination diet in which food products containing gluten are avoided.