Corpus ID: 35821921

Patients: A Meta-analysis of Prospective Studies Incidence of Adverse Drug Reactions in Hospitalized

  title={Patients: A Meta-analysis of Prospective Studies Incidence of Adverse Drug Reactions in Hospitalized},
  author={Jason Lazarou and Bruce H. Pomeranz and Paul N. Corey and D. Bates and Related Letters},
7 Citations
Biopiracy versus One-World Medicine-From colonial relicts to global collaborative concepts.
  • T. Efferth, Mita Banerjee, +38 authors N. Paul
  • Medicine, Political Science
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
  • 2019
The concept of integrative medicine attempts to combine holistic CAM approaches with evidence-based principles of conventional medicine to realize the concept of One-World Medicine. Expand
Investigating the adverse effects of novel tumour-specific IAP antagonists
The results allowed us to assess the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals, not necessarily belonging to the same breeds. Expand
Systematic Analysis of Adverse Event Reports for Sex Differences in Adverse Drug Events
This study detected among 668 drugs of the most frequent 20 treatment regimens in the United States, 307 drugs have sex differences in ADEs and identified 736 unique drug-event combinations with significant sex differences. Expand
Identifying Adverse Drug Events by Relational Learning
This paper casts the problem of post-marketing surveillance of drugs to identify previously-unanticipated ADEs as a reverse machine learning task, related to relational subgroup discovery and provides an initial evaluation of this approach based on experiments with an actual EMR/EHR and known adverse drug events. Expand
Multi-task and Multi-view Learning for Predicting Adverse Drug Reactions
This work proposes a set of statistical learning models for effective ADRs prediction systematically from multiple perspectives, and proposes two multi-task learning (MTL) algorithms for jointly predicting active compounds of multiple proteins, and these methods outperform existing states of the art significantly. Expand
Adverse drug reactions in internal medicine units and associated risk factors
A significant prevalence of ADRs was found among hospitalized patients, and duration of hospital admission, changes in renal status during hospitalization and drug interactions seem to be important risk factors for ADRs. Expand
Myopathy with statin–fibrate combination therapy: clinical considerations
Clinicians need to consider pharmacokinetic, pharmacodynamic, metabolic, pathophysiologic and other factors that can increase the systemic exposure of statins and/or fibrates and hence heighten the risk of toxic effects on muscles, as well as data from clinical trials and recommendations of consensus panels to optimize the safety of such combination regimens. Expand


Thalidomide revisited.
Studies on the epidemiology of adverse drug reactions, III: reactions in patients on a general medical service
  • Johns Hopkins Hosp Bull
  • 1966
Most often, adverse drug reactions are not severe, but the predictability of seriousness usually is not possible, and when reactions occur they are unexpected. Expand
Incidence and preventability of adverse drug events in hospitalized adults
It is concluded that ADEs are not infrequent, often preventable, and usually caused by physician decisions and Optimal prevention strategies should cover many types of drugs and target physicians’ ordering practices. Expand
Relationship between medication errors and adverse drug events
Medication errors are common, although relatively few result in ADEs, however, those that do are preventable, many through physician computer order entry. Expand
The hazards of hospitalization*
The occurrence of hospital-induced complications on a university medical service was documented in the prospective investigation of over 1000 patients and the severity of the reported episodes was minor in 110, moderate in 82, and major in 48, of which 16 ended fatally. Expand
Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality.
The attributable lengths of stay and costs of hospitalization for ADEs are substantial and an ADE is associated with a significantly prolonged length of stay, increased economic burden, and an almost 2-fold increased risk of death. Expand
Reporting of adverse events in hospitals in Victoria 1994‐1995
  • B. Collopy
  • Medicine
  • The Medical journal of Australia
  • 1997
The prevalence of overweight and obesity in children attending general practices in western Sydney and the main outcome measure was children's body mass index (BMI) was calculated as weightlheight squared. Expand
The costs of adverse drug events in hospitalized patients
The substantial costs of ADEs to hospitals justify investment in efforts to prevent these events, and estimates of annual costs attributable to all ADEs and preventable ADEs for a 700-bed teaching hospital are $5.6 million and $2.8 million are conservative because they do not include the costs of injuries to patients or malpractice costs. Expand
Bill would force drug makers to give cus - tomersdataonrisks
  • NewYorkTimes . July 25 ,
  • 1996