Patient specific treatment planning for systemically administered radiopharmaceuticals using PET/CT and Monte Carlo simulation.
@article{Grudzinski2010PatientST, title={Patient specific treatment planning for systemically administered radiopharmaceuticals using PET/CT and Monte Carlo simulation.}, author={J. Grudzinski and H. Yoriyaz and P. Deluca and J. Weichert}, journal={Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine}, year={2010}, volume={68 1}, pages={ 59-65 } }
The efficacy of systemically administered radiopharmaceuticals depends on the physiological path of the targeting molecule and the physical characteristics of the attached radionuclide. NM404 is a candidate for patient specific dosimetry because it can be used concurrently for both diagnosis and therapy. Radiolabeling NM404 with [(124)I] affords the possibility of performing noninvasive PET imaging while [(131)I] allows for radiotherapy. Patient specific dosimetry for radiation treatment… CONTINUE READING
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