Patient-specific thresholds of intracranial pressure in severe traumatic brain injury.

  title={Patient-specific thresholds of intracranial pressure in severe traumatic brain injury.},
  author={Christos Lazaridis and Stacia DeSantis and Peter Smielewski and David K. Menon and Peter J. A. Hutchinson and John D. Pickard and Marek Czosnyka},
  journal={Journal of neurosurgery},
  volume={120 4},
OBJECT Based on continuous monitoring of the pressure reactivity index (PRx), the authors defined individualized intracranial pressure (ICP) thresholds by graphing the relationship between ICP and PRx. These investigators hypothesized that an "ICP dose" based on individually assessed ICP thresholds would correlate more closely with the 6-month outcome when compared with ICP doses derived by the recommended universal thresholds of 20 and 25 mm Hg. METHODS This study was a retrospective… CONTINUE READING
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