Patient Satisfaction and Safety With Aesthetic OnabotulinumtoxinA After At Least 5 Years: A Retrospective Cross-Sectional Analysis of 4,402 Glabellar Treatments

@article{TrindadedeAlmeida2015PatientSA,
  title={Patient Satisfaction and Safety With Aesthetic OnabotulinumtoxinA After At Least 5 Years: A Retrospective Cross-Sectional Analysis of 4,402 Glabellar Treatments},
  author={Ada Regina Trindade de Almeida and Jean D. A. Carruthers and Sue Ellen Cox and Mitchel P. Goldman and Sarah Wheeler and Conor J. Gallagher},
  journal={Dermatologic Surgery},
  year={2015},
  volume={41},
  pages={S19–S28}
}
BACKGROUND Despite extensive clinical experience with onabotulinumtoxinA, few data exist on patient satisfaction or safety with continuous treatment. OBJECTIVE This international multicenter study evaluated patient satisfaction and safety with long-term continuous facial aesthetic treatment with onabotulinumtoxinA. METHODS Retrospective chart review with a cross-sectional design was used to assess onabotulinumtoxinA treatment, including dosing, concomitant facial aesthetic medications and… 
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Subject Satisfaction With OnabotulinumtoxinA Treatment of Glabellar and Lateral Canthal Lines Using a New Patient-Reported Outcome Measure
TLDR
High satisfaction rates are achieved and sustained in subjects treated with onabotulinumtoxinA for GL and CFL combined, and aesthetic improvement was observed in most subjects at Days 30 and 60, respectively.
OnabotulinumtoxinA for Treatment of Forehead and Glabellar Lines: Subject-Reported Satisfaction and Impact From a Phase 3 Double-Blind Study
TLDR
Subjects were highly satisfied with onabotulinumtoxinA treatment and reported significant improvements in appearance-related psychological and emotional impacts of their facial lines.
Pooled Subject-Reported Outcomes From 2 Phase 3 Studies of OnabotulinumtoxinA for Simultaneous Treatment of Forehead and Glabellar Lines.
TLDR
This study demonstrates a high level of treatment satisfaction and significantly improved appearance-related psychological outcomes among toxin-naive subjects after onabotulinumtoxinA 40 U treatment.
Evolution of Facial Aesthetic Treatment Over Five or More Years: A Retrospective Cross-sectional Analysis of Continuous OnabotulinumtoxinA Treatment
TLDR
OnabotulinumtoxinA treatment evolved over time, coinciding with growth of the facial aesthetics market and by facial area corresponding with increases in treatments with injectable fillers, energy-based devices, and prescription topical creams.
OnabotulinumtoxinA for Simultaneous Treatment of Upper Facial Lines: Subject-Reported Satisfaction and Impact From a Phase 3 Study.
TLDR
OnabotulinumtoxinA treatment was associated with high subject satisfaction and significant improvements in appearance-related psychological and emotional impacts.
Adverse Events of Botulinum Toxin Type A in Facial Rejuvenation: A Systematic Review and Meta-Analysis
TLDR
This meta-analysis confirmed the safety profile of BTx-A for glabellar and crow’s feet lines, and BTX-A usage for the removal of upper facial wrinkles, which have some significant mild-to-moderate adverse profiles, including headache, eye disorder, eyelid ptosis, and heavy eyelids.
Safety and Efficacy of OnabotulinumtoxinA for Treatment of Crow’s Feet Lines in Chinese Subjects
TLDR
OnabotulinumtoxinA 24 U was effective and well tolerated for the treatment of CFL in Chinese subjects, with responses maintained over 5 months and a low occurrence of treatment-related adverse events.
Forehead Line Treatment With OnabotulinumtoxinA in Subjects With Forehead and Glabellar Facial Rhytids: A Phase 3 Study
  • S. Fagien, Joel L Cohen, +9 authors C. Mao
  • Medicine
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • 2017
TLDR
OnabotulinumtoxinA 40 U distributed between the frontalis and glabellar complex was safe and effective for treatment of moderate-to-severe FHL.
Impact of Comprehensive, Minimally Invasive, Multimodal Aesthetic Treatment on Satisfaction With Facial Appearance: The HARMONY Study
TLDR
Minimally invasive, multimodal treatment resulted in improvements in FACE-Q scores and perceived age, indicating a high degree of patient satisfaction and a younger facial appearance.
Multimodal Facial Aesthetic Treatment on the Appearance of Aging, Social Confidence, and Psychological Wellbeing: HARMONY Study.
TLDR
Multimodal, full facial aesthetic treatment improves patients' self-reported psychological well-being, social confidence, aging appearance, and perceptions of chronologic age.
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