Pathways to neurodegeneration: effects of HIV and aging on resting-state functional connectivity.

@article{Thomas2013PathwaysTN,
  title={Pathways to neurodegeneration: effects of HIV and aging on resting-state functional connectivity.},
  author={Jewell B. Thomas and Matthew R. Brier and Abraham Z. Snyder and Florin Vaida and Beau M. Ances},
  journal={Neurology},
  year={2013},
  volume={80 13},
  pages={1186-93}
}
OBJECTIVE Resting-state functional connectivity MRI (rs-fcMRI) may provide insight into the neurophysiology of HIV and aging. METHODS In this cross-sectional study, we used rs-fcMRI to investigate intra- and internetwork connectivity among 5 functional brain networks in 58 HIV-infected (HIV+) participants (44% receiving highly active antiretroviral therapy) and 53 HIV-uninfected (HIV-) controls. An analysis of covariance assessed the relationship among age, HIV laboratory markers, or degree… CONTINUE READING
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