Pathways change in expression during replicative aging in Saccharomyces cerevisiae.

@article{Yiu2008PathwaysCI,
  title={Pathways change in expression during replicative aging in Saccharomyces cerevisiae.},
  author={Gloria Yiu and Alejandra E. McCord and Alison Wise and Rishi Jindal and Jennifer Hardee and Allen C. Kuo and Michelle Yuen Shimogawa and Laty A. Cahoon and Michelle X.Y. Wu and John Kloke and Johanna Hardin and Laura L. Mays Hoopes},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={2008},
  volume={63 1},
  pages={21-34}
}
Yeast replicative aging is a process resembling replicative aging in mammalian cells. During aging, wild-type haploid yeast cells enlarge, become sterile, and undergo nucleolar enlargement and fragmentation; we sought gene expression changes during the time of these phenotypic changes. Gene expression studied via microarrays and quantitative real-time… CONTINUE READING