Pathway of proton transfer in bacterial reaction centers: role of aspartate-L213 in proton transfers associated with reduction of quinoneto dihydroquinone.

@article{Paddock1994PathwayOP,
  title={Pathway of proton transfer in bacterial reaction centers: role of aspartate-L213 in proton transfers associated with reduction of quinoneto dihydroquinone.},
  author={Mark L. Paddock and Scott H. Rongey and Paul H McPherson and A Juth and George Feher and Melvin Y Okamura},
  journal={Biochemistry},
  year={1994},
  volume={33 3},
  pages={734-45}
}
The role of Asp-L213 in proton transfer to reduced quinone QB in the reaction center (RC) from Rhodobacter sphaeroides was studied by site-directed replacement of Asp with residues having different proton donor properties. Reaction centers (RCs) with Asn, Leu, Thr, and Ser at L213 had greatly reduced (approximately 6000-fold) proton-coupled electron transfer [kAB(2)] and proton uptake rates associated with the second electron reduction of QB (QA- QB- + 2H(+)-->QAQBH2) compared to native RCs… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Chance and design--proton transfer in water, channels and bioenergetic proteins.

Biochimica et biophysica acta • 2006
View 4 Excerpts
Highly Influenced

George Feher: a pioneer in reaction center research

Photosynthesis Research • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…