Pathway knockout and redundancy in metabolic networks.


The robustness and stability of complex cellular networks is often attributed to the redundancy of components, including genes, enzymes and pathways. Estimation of redundancy is still an open question in systems biology. Current theoretical tools to measure redundancy have various strengths and shortcomings in providing a comprehensive description of… (More)
DOI: 10.1016/j.jtbi.2010.11.012


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