Pathway analysis of bladder cancer genome-wide association study identifies novel pathways involved in bladder cancer development

@inproceedings{Chen2016PathwayAO,
  title={Pathway analysis of bladder cancer genome-wide association study identifies novel pathways involved in bladder cancer development},
  author={Meng Zhu Chen and Nathaniel Rothman and Yuanqing Ye and Jian Gu and Paul Scheet and Maosheng Huang and David W Chang and Colin P. N. Dinney and Debra T. Silverman and Jonine D Figueroa and Stephen J. Chanock and Xifeng Wu},
  booktitle={Genes & cancer},
  year={2016}
}
Genome-wide association studies (GWAS) are designed to identify individual regions associated with cancer risk, but only explain a small fraction of the inherited variability. Alternative approach analyzing genetic variants within biological pathways has been proposed to discover networks of susceptibility genes with additional effects. The gene set enrichment analysis (GSEA) may complement and expand traditional GWAS analysis to identify novel genes and pathways associated with bladder cancer… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 50 REFERENCES

Cancer statistics ,

A. Jemal
  • CA Cancer J Clin
  • 2015

Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes.

  • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • 2012