Pathophysiology of tumor progression in human gallbladder: flow cytometry, CEA, and CA 19-9 levels in bile and serum in different stages of gallbladder disease.

@article{Strom1989PathophysiologyOT,
  title={Pathophysiology of tumor progression in human gallbladder: flow cytometry, CEA, and CA 19-9 levels in bile and serum in different stages of gallbladder disease.},
  author={Brian L. Strom and Dimitrios C. Iliopoulos and Barbara Atkinson and Meenhard Herlyn and Suzanne L. West and Greg Maislin and Shura Saul and Michael A Varello and H{\'e}ctor Abelardo Rodr{\'i}guez-Mart{\'i}nez and J L Rios-Dalenz},
  journal={Journal of the National Cancer Institute},
  year={1989},
  volume={81 20},
  pages={1575-80}
}
Gallbladder epithelium is unique among the gastrointestinal cell types because proteins and protein levels in the fluid bathing the luminal side of the cells (bile) are different from and can be compared with those in the fluid bathing the basal side (serum). To help identify cellular changes that occur during the development of gallbladder cancer, we obtained gallbladder tissue, serum, and bile specimens from 20 patients with invasive adenocarcinoma of the gallbladder, three with high-grade… CONTINUE READING