Pathophysiology of spastic paresis. II: Emergence of muscle overactivity.

@article{Gracies2005PathophysiologyOS,
  title={Pathophysiology of spastic paresis. II: Emergence of muscle overactivity.},
  author={Jean-Michel Gracies},
  journal={Muscle & nerve},
  year={2005},
  volume={31 5},
  pages={552-71}
}
In the subacute and chronic stages of spastic paresis, stretch-sensitive (spastic) muscle overactivity emerges as a third fundamental mechanism of motor impairment, along with paresis and soft tissue contracture. Part II of this review primarily addresses the pathophysiology of the various forms of spastic overactivity. It is argued that muscle contracture is one of the factors that cause excessive responsiveness to stretch, which in turn aggravates contracture. Excessive responsiveness to… CONTINUE READING

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