Pathophysiology of pulmonary hypertension in acute lung injury.

  title={Pathophysiology of pulmonary hypertension in acute lung injury.},
  author={Laura Claire Price and D F Mcauley and Philip S Marino and Simon J. Finney and Mark J. D. Griffiths and Stephen John Wort},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  volume={302 9},
Acute lung injury (ALI) and acute respiratory distress syndrome are characterized by protein rich alveolar edema, reduced lung compliance, and acute severe hypoxemia. A degree of pulmonary hypertension (PH) is also characteristic, higher levels of which are associated with increased morbidity and mortality. The increase in right ventricular (RV) afterload causes RV dysfunction and failure in some patients, with associated adverse effects on oxygen delivery. Although the introduction of lung… CONTINUE READING
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