Pathophysiology of placenta creta: the role of decidua and extravillous trophoblast.

@article{Tantbirojn2008PathophysiologyOP,
  title={Pathophysiology of placenta creta: the role of decidua and extravillous trophoblast.},
  author={Patou Tantbirojn and Christopher P Crum and Mana M Parast},
  journal={Placenta},
  year={2008},
  volume={29 7},
  pages={639-45}
}
Placenta creta is associated with massive postpartum hemorrhage and commonly leads to emergency hysterectomy. While the exact pathogenesis of placenta creta is unknown, proposed hypotheses include a primary deficiency of decidua, abnormal maternal vascular remodeling, excessive trophoblastic invasion, or a combination thereof. To assess these changes in placenta creta, we retrospectively reviewed 49 cases of gravid hysterectomy, 38 with and 11 without the diagnosis of creta, gathered clinical… CONTINUE READING

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