Pathophysiology of peri-articular bone changes in osteoarthritis.

@article{Weinans2012PathophysiologyOP,
  title={Pathophysiology of peri-articular bone changes in osteoarthritis.},
  author={Harrie Weinans and Michiel Siebelt and Rintje Agricola and Sander M. Botter and Tom M Piscaer and Jan Hendrik Waarsing},
  journal={Bone},
  year={2012},
  volume={51 2},
  pages={190-6}
}
Osteoarthritis (OA) is a disease that involves the entire joint, but its pathophysiology is not well described. Alterations in peri-articular bone are an integral part of the OA disease process and different aspects of bone changes have been described in different patient (sub)groups and animal models. In this review we will discuss the osteoarthritis pathophysiology from the perspective of periarticular bone changes, which can be considered at three hierarchical levels: the bone (or joint… CONTINUE READING
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The association between hip morphology parameters and nineteen-year risk of end-stage osteoarthritis of the hip: a nested case-control study. Arthritis Rheum 2011;63:3392–400

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