Pathophysiology of meningococcal sepsis in children

  title={Pathophysiology of meningococcal sepsis in children},
  author={Enitan D Carrol and Paul Baines and Alistair Thomson and Charles A. Hart},
  journal={European Journal of Pediatrics},
UNLABELLED Septic shock with purpura is a syndrome frequently diagnosed in children and predominantly caused by Neisseria meningitidis. Despite improvements in management and therapy the mortality and morbidity in these patients are still high. During the last few years much effort has been put into understanding of the systemic host response during this acute infectious disease. This host response can be divided into the process of recognition of endotoxin, the cascade of pro- and counter… CONTINUE READING