Pathophysiology of ischemic acute kidney injury

@article{Sharfuddin2011PathophysiologyOI,
  title={Pathophysiology of ischemic acute kidney injury},
  author={A. Sharfuddin and B. Molitoris},
  journal={Nature Reviews Nephrology},
  year={2011},
  volume={7},
  pages={189-200}
}
Acute kidney injury (AKI) as a consequence of ischemia is a common clinical event leading to unacceptably high morbidity and mortality, development of chronic kidney disease (CKD), and transition from pre-existing CKD to end-stage renal disease. Data indicate a close interaction between the many cell types involved in the pathophysiology of ischemic AKI, which has critical implications for the treatment of this condition. Inflammation seems to be the common factor that links the various cell… Expand
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