Pathophysiology of idiopathic dystonia: findings from genetic animal models

@article{Richter1998PathophysiologyOI,
  title={Pathophysiology of idiopathic dystonia: findings from genetic animal models},
  author={Angelika Richter and Wolfgang L{\"o}scher},
  journal={Progress in Neurobiology},
  year={1998},
  volume={54},
  pages={633-677}
}
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114 Citations
Highly Influential Citations
2
Background Citations
30
Methods Citations
9
Results Citations
4

114 Citations

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It was found that partial selective pharmacological block of the sodium pumps in the cerebellum and basal ganglia of mice recapitulates all of the salient features of DYT12, including dystonia and parkinsonism induced by stress.
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The functional neuroanatomy of dystonia
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Experimental therapeutics for dystonia
Rodent models for dystonia research: Characteristics, evaluation, and utility
TLDR
A recent workshop addressed four main issues affecting those who conduct dystonia research with animal models, including the different ways in which dystonic disorders can be modeled in rodents, key features that constitute a useful model, methods used in the evaluation of these models, and recommendations for future research.
CHAPTER C4 – Mouse Models of Dystonia
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