Pathophysiology of hepatic encephalopathy.

  • P Ferenci
  • Published 1991 in Hepato-gastroenterology


Changes in various neurotransmitter systems, in blood brain barrier integrity and/or function, and in brain energy metabolism, may precipitate HE. Although a "specific cause" of HE (i.e. the presence of a well-defined toxin) has not been identified so far, the common denominator of all these changes is the presence of liver failure. The various hypotheses… (More)