Pathophysiology of heart failure: identifying targets for pharmacotherapy.

  title={Pathophysiology of heart failure: identifying targets for pharmacotherapy.},
  author={Arnold M. Katz},
  journal={The Medical clinics of North America},
  volume={87 2},
Recent advances in our understanding of the pathophysiology of heart failure have greatly increased the number of potential targets for therapy. The most important of these advances was the recognition that a major goal of therapy should be to modify long-term proliferative responses, as well as to achieve short-term functional improvement. This conclusion emerged from several clinical trials which showed that correction of functional abnormalities in these patients, although often of immediate… CONTINUE READING


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