Pathophysiology of gastro-esophageal reflux disease: a role for mucosa integrity?

  • Richard Farré
  • Published 2013 in
    Neurogastroenterology and motility : the official…

Abstract

BACKGROUND Gastro-esophageal reflux disease (GERD) is very prevalent and has a high burden on health security system costs. Nevertheless, pathophysiology is complex and not well-understood. Several mechanisms have been proposed: decreased salivation, impaired esophageal clearance, decreased lower esophageal sphincter pressure resting tone, presence of… (More)
DOI: 10.1111/nmo.12201

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