Pathophysiology of functional heartburn based on Rome III criteria in Japanese patients.

Abstract

AIM To investigate the pathophysiology of functional heartburn (FH) in Japanese patients. METHODS A total of 111 patients with proton pump inhibitor (PPI)-refractory non-erosive gastroesophageal reflux disease underwent intraesophageal pressure testing and 24-h multichannel intraluminal impedance-pH (24MII-pH) testing. The patients also completed several… (More)
DOI: 10.3748/wjg.v21.i16.5009

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