Pathophysiology of drug-induced papillary necrosis.

  • Selina Sabatini
  • Published 1984 in
    Fundamental and applied toxicology : official…


Papillary necrosis, a common cause of renal failure, is a life-threatening pathophysiologic event which may have a multiplicity of mechanisms. The primary functional lesions are salt wastage, impairment of urinary concentrating ability, polyuria, and imbalances of potassium, calcium and phosphate homeostasis; urinary acidification is completely normal… (More)


Cite this paper

@article{Sabatini1984PathophysiologyOD, title={Pathophysiology of drug-induced papillary necrosis.}, author={Selina Sabatini}, journal={Fundamental and applied toxicology : official journal of the Society of Toxicology}, year={1984}, volume={4 6}, pages={909-21} }