Pathophysiology of coronary artery disease.

@article{Libby2005PathophysiologyOC,
  title={Pathophysiology of coronary artery disease.},
  author={Peter Libby and Pierre Th{\'e}roux},
  journal={Circulation},
  year={2005},
  volume={111 25},
  pages={3481-8}
}
During the past decade, our understanding of the pathophysiology of coronary artery disease (CAD) has undergone a remarkable evolution. We review here how these advances have altered our concepts of and clinical approaches to both the chronic and acute phases of CAD. Previously considered a cholesterol storage disease, we currently view atherosclerosis as an inflammatory disorder. The appreciation of arterial remodeling (compensatory enlargement) has expanded attention beyond stenoses evident… CONTINUE READING
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