Pathophysiology of cerebral ischemia and brain trauma: similarities and differences.

@article{Bramlett2004PathophysiologyOC,
  title={Pathophysiology of cerebral ischemia and brain trauma: similarities and differences.},
  author={Helen M. Bramlett and W. Dalton Dietrich},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2004},
  volume={24 2},
  pages={133-50}
}
Current knowledge regarding the pathophysiology of cerebral ischemia and brain trauma indicates that similar mechanisms contribute to loss of cellular integrity and tissue destruction. Mechanisms of cell damage include excitotoxicity, oxidative stress, free radical production, apoptosis and inflammation. Genetic and gender factors have also been shown to be important mediators of pathomechanisms present in both injury settings. However, the fact that these injuries arise from different types of… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS