Pathophysiology of acute brain dysfunction: what's the cause of all this confusion?

@article{Hughes2012PathophysiologyOA,
  title={Pathophysiology of acute brain dysfunction: what's the cause of all this confusion?},
  author={C. Hughes and M. Patel and P. Pandharipande},
  journal={Current Opinion in Critical Care},
  year={2012},
  volume={18},
  pages={518–526}
}
  • C. Hughes, M. Patel, P. Pandharipande
  • Published 2012
  • Medicine
  • Current Opinion in Critical Care
  • Purpose of reviewTo survey the recent medical literature examining the pathophysiology of acute brain dysfunction (delirium and coma) in the ICU. Recent findingsClinical risk factors for brain dysfunction in the ICU continue to be elucidated and prediction models developed. Multiple studies have identified sedatives, especially benzodiazepines, as modifiable risk factors for delirium. Imaging studies examining global brain disorders have demonstrated white matter lesions and brain atrophy to be… CONTINUE READING
    Delirium in elderly people
    • 1,305
    • PDF
    A clinical perspective of sepsis-associated delirium
    • 42
    Knowns and Unknowns About Delirium in Stroke: A Review
    • 11
    Do nutrients play a role in delirium?
    • 15
    Postoperative delirium.
    • 99
    • PDF

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 78 REFERENCES
    The neuroinflammatory hypothesis of delirium
    • 224
    • PDF
    Is there a final common neural pathway in delirium? Focus on acetylcholine and dopamine.
    • 214
    Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence.
    • 340
    • Highly Influential
    • PDF
    Evidence for a cytokine model of cognitive function
    • 543
    • PDF
    Cerebral perfusion in sepsis-associated delirium
    • 160
    • PDF