Pathophysiology and pharmacology of migraine. Is there a place for antiemetics in future treatment strategies?

@article{Dahlf1998PathophysiologyAP,
  title={Pathophysiology and pharmacology of migraine. Is there a place for antiemetics in future treatment strategies?},
  author={Carl G. H. Dahl{\"o}f and Richard J. Hargreaves},
  journal={Cephalalgia : an international journal of headache},
  year={1998},
  volume={18 9},
  pages={593-604}
}
This article reviews the pathophysiology and pharmacology of emesis in relation to migraine pathogenesis. Also, the place of antiemetic and gastrointestinal prokinetic agents in current and future acute migraine treatment strategies is reviewed. The mechanisms of action of current and novel acute migraine therapies are considered with respect to the neurogenic and vascular hypothesis. Control of migraine-associated nausea and vomiting is often achieved with the benzamide dopamine D2 receptor… CONTINUE READING

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