Pathophysiological variability of different genotypes of human Blastocystis hominis Egyptian isolates in experimentally infected rats

@article{Hussein2007PathophysiologicalVO,
  title={Pathophysiological variability of different genotypes of human Blastocystis hominis Egyptian isolates in experimentally infected rats},
  author={Eman M Hussein and Abdalla M. Hussein and Mohamed M. Eida and Maha M. Atwa},
  journal={Parasitology Research},
  year={2007},
  volume={102},
  pages={853-860}
}
The genotyping of Blastocystis hominis clinical isolates obtained from 28 gastrointestinal symptomatic patients and 16 asymptomatic individuals were identified by polymerase chain reaction using sequenced-tagged site (STS) primers. Then, pathophysiological variability between different B. hominis genotypes was evaluated in experimentally infected rats. Only four B. hominis subtypes (1, 2, 3, and 4) were detected (18.2%, 9.1%, 54.5%, and 18.2%, respectively) in human isolates. In symptomatic… Expand
A possible link between subtype 2 and asymptomatic infections of Blastocystis hominis
TLDR
The present study suggests that subtype 2 is a non-pathogenic genotype of B. hominis, one of the most common eukaryotic organisms in the intestinal tract of humans, while its pathogenic potential is still controversial. Expand
Genetic variability of Blastocystis sp. isolated from symptomatic and asymptomatic individuals in Iran
TLDR
In this study, ST1 in gastrointestinal patients compared to asymptomatic individuals was significantly dominant and significantly related to GI symptoms, and eight mixed infections with three different STs, which are under reported, were also identified. Expand
Proteaese activity of Blastocystis hominis subtype3 in symptomatic and asymptomatic patients
TLDR
It was concluded that proteases of B. hominis genetic subtype 3, particularly those at 32 kDa, could be considered a virulence factor that is responsible for protein degradation and have a possible pathogenic role in host immune evasion. Expand
Molecular epidemiology of human Blastocystis isolates in France
TLDR
This study determined the frequency of different Blastocystis subtypes in patients in France and hypothesized on the mode of transmission and tested a possible relationship between the subtype and symptomatic status. Expand
Subtype identification of Blastocystis spp. isolated from patients in a major hospital in northeastern Thailand
The present study is aimed to identify the prevalence of Blastocystis subtypes isolated from patients in a major hospital in northeastern Thailand. A total of 562 stool samples were examined byExpand
Prevalence and Subtype Analysis of Blastocystis hominis Isolated from Patients in the Northeast of Iran
TLDR
In this study, ST7 had a low prevalence in the northeast of Iran, and similar to previous studies, ST3 was the dominant subtype. Expand
Association of Blastocystis hominis genetic subtypes with urticaria
TLDR
It was concluded that acute Urticaria of unknown etiology and chronic idiopathic urticaria patients who are resistant to the ordinary regimen of urticarial treatment might be examined for infection with B. hominis, in order to prescribe the proper specific anti-protozoan treatment. Expand
The pathogenic role of different Blastocystis hominis genotypes isolated from patients with irritable bowel syndrome.
TLDR
Genotype I was the most pathogenic genotype of B. hominis isolates in patients with IBS while genotype II was not detected among those patients, and the results suggest the presence of pathogenic and non-pathogenic strains among genotypes III and IV. Expand
Blastocystis subtypes isolated from travelers and non-travelers from the North of Poland.
  • M. Rudzińska, B. Kowalewska, P. Wąż
  • Medicine, Biology
  • Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
  • 2019
TLDR
This study sheds more light on the issue of Blastocystis infection import and shows that data on the travel history of the persons surveyed are necessary for clarification of which STs detected in Europe are indigenous and which ones could have been imported due to travel or migration. Expand
Molecular epidemiology of Blastocystis in Lebanon and correlation between subtype 1 and gastrointestinal symptoms.
TLDR
The first data concerning the prevalence of this parasite and the frequency of the Blastocystis subtypes (STs) in the Lebanese population were acquired and these data were compared with those available in other Middle Eastern and neighboring countries. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 55 REFERENCES
Genetic variability of Blastocystis hominis isolates in China
TLDR
The results showed that subtype 1 was more a popular genotype in China than other B. hominis subtypes obtained from five geographically different countries, suggesting a possible relationship between sub type 1 and a pathogenic potential of this parasite. Expand
Infectivity of different genotypes of human Blastocystis hominis isolates in chickens and rats.
TLDR
It is confirmed that several genotypes from human isolates could infect chickens and/or rats, indicating that chickens and rats are suitable experimental animal models for studying the zoonotic potential of human Blastocystis isolates. Expand
Polymerase chain reaction-based genotype classification among human Blastocystis hominis populations isolated from different countries
TLDR
PCR-based genotype classification is a powerful tool with which to analyse genotypes of Blastocystis isolates obtained from clinical samples and it could not be shown that the specific genotype correlated with the pathogenic potential of B. hominis. Expand
Isoenzyme patterns of Blastocystis hominis patient isolates derived from symptomatic and healthy carriers
Isolates of Blastocystis hominis derived from patients with intestinal symptoms and from healthy carriers were cultured in vitro and isoenzyme patterns of hexokinase (E.C. 2.7.1.1),Expand
Ribodemes of Blastocystis hominis isolated in Japan.
TLDR
The results suggest that ribodemes I, III, and VI may be responsible for gastrointestinal symptoms and a possible relationship between ribodeme type and pathogenicity. Expand
Soluble-protein and antigenic heterogeneity in axenic Blastocystis hominis isolates: pathogenic implications
TLDR
The protein and antigenic heterogeneity of B. hominis is confirmed and the existence of demes with different pathogenic roles is confirmed, including two related antigenic groups found in double-immunodiffusion and Western-blot studies. Expand
Pathogenicity of Blastocystis hominis, a clinical reevaluation.
TLDR
Intestinal symptoms may be seen frequently together with the presence of B. hominis and this protozoan may be regarded as an intestinal pathogen, especially when other agents are eliminated. Expand
Epidemiologic survey of Blastocystis hominis infection in Japan.
TLDR
It seems that infection with B. hominis rarely gives rise to clinical symptoms, and the prevalence in the Japanese was lower than in the non-Japanese, and lower than the prevalence reported for other countries. Expand
Prevalence and clinical relevance of Blastocystis hominis in diverse patient cohorts
TLDR
A prevalence study to investigate the association between the presence of several intestinal parasites and gastrointestinal symptoms in diverse patient cohorts showed a high prevalence of parasites in all the risk groups and B. hominis was the parasite most frequently detected in each studied group. Expand
Predominance of amoeboid forms of Blastocystis hominis in isolates from symptomatic patients
TLDR
The amoeboid form could either be an indicator of pathogenicity of B. hominis, or the form likely to contribute to pathogenicicity and be responsible for the symptoms seen in patients. Expand
...
1
2
3
4
5
...