Pathophysiological determinants of worse stroke outcome in atrial fibrillation.

  title={Pathophysiological determinants of worse stroke outcome in atrial fibrillation.},
  author={Hans T H Tu and Bruce C V Campbell and Soren Christensen and Marnie Collins and Deidre Anne De Silva and K. Scott Butcher and Mark William Parsons and Patricia M. Desmond and Philip A. Barber and Christopher Royce Levi and Christopher F. Bladin and Geoffrey Alan Donnan and Stephen M Davis},
  journal={Cerebrovascular diseases},
  volume={30 4},
BACKGROUND The reasons for worse outcome following ischemic stroke in patients with atrial fibrillation (AF) remain unclear. We aimed to elucidate the pathophysiological determinants of poorer stroke outcome in patients with AF using systematic MRI data from the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET). METHODS Comparisons of infarct size, hypoperfusion volume, infarct growth, arterial occlusion, recanalization, reperfusion, hemorrhagic transformation and stroke severity… CONTINUE READING


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