Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure.

@article{Kitzman2002PathophysiologicalCO,
  title={Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure.},
  author={Dalane W. Kitzman and William James Little and Peter H. Brubaker and Roger T. Anderson and W. Gregory Hundley and Christian T Marburger and Bridget K Brosnihan and Timothy M. Morgan and Kathryn P. Stewart},
  journal={JAMA},
  year={2002},
  volume={288 17},
  pages={
          2144-50
        }
}
CONTEXT Many older patients with symptoms of congestive heart failure have a preserved left ventricular ejection fraction (LVEF). However, the pathophysiology of this disorder, presumptively termed diastolic heart failure (DHF), is not well characterized and it is unknown whether it represents true heart failure. OBJECTIVE To assess the 4 key pathophysiological domains that characterize classic heart failure by systematically performing measurements in older patients with presumed DHF and… CONTINUE READING
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