Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric Disorders

  title={Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric Disorders},
  author={Heeok Hong and Byung Sun Kim and Heh-In Im},
  booktitle={International neurourology journal},
Brain diseases and disorders such as Alzheimer disease, Parkinson disease, depression, schizophrenia, autism, and addiction lead to reduced quality of daily life through abnormal thoughts, perceptions, emotional states, and behavior. While the underlying mechanisms remain poorly understood, human and animal studies have supported a role of neuroinflammation in the etiology of these diseases. In the central nervous system, an increased inflammatory response is capable of activating microglial… CONTINUE READING
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