Pathophysiological Basis for Antioxidant Therapy in Chronic Liver Disease

  title={Pathophysiological Basis for Antioxidant Therapy in Chronic Liver Disease},
  author={Jes{\'u}s Medina and Dr Ricardo Moreno-Otero},
Oxidative stress is a common pathogenetic mechanism contributing to initiation and progression of hepatic damage in a variety of liver disorders. Cell damage occurs when there is an excess of reactive species derived from oxygen and nitrogen, or a defect of antioxidant molecules. Experimental research on the delicately regulated molecular strategies whereby cells control the balance between oxidant and antioxidant molecules has progressed in recent years. On the basis of this evidence… CONTINUE READING


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