Pathophysiologic basis of acute respiratory distress in patients who fail a trial of weaning from mechanical ventilation.
@article{Jubran1997PathophysiologicBO, title={Pathophysiologic basis of acute respiratory distress in patients who fail a trial of weaning from mechanical ventilation.}, author={A. Jubran and M. Tobin}, journal={American journal of respiratory and critical care medicine}, year={1997}, volume={155 3}, pages={ 906-15 } }
To determine the mechanisms of acute respiratory distress and failure in patients with chronic obstructive pulmonary disease (COPD), we studied 17 ventilator-supported patients who failed a trial of spontaneous breathing and 14 patients who tolerated such a trial and were successfully extubated. Immediately before the weaning trials, maximal inspiratory pressure was not statistically different between the two groups (p = 0.48). On discontinuation of the ventilator, the failure group immediately… CONTINUE READING
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Partially assisted mechanical ventilation is ideally titrated to maintain adequate
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