Pathophysiologic, morphometric, and biochemical studies of the premature baboon with bronchopulmonary dysplasia.

@article{Coalson1992PathophysiologicMA,
  title={Pathophysiologic, morphometric, and biochemical studies of the premature baboon with bronchopulmonary dysplasia.},
  author={Jacqueline J. Coalson and Vicki T. Winter and Dale R. Gerstmann and Steven Idell and Raymond J. R. King and Robert A Delemos},
  journal={The American review of respiratory disease},
  year={1992},
  volume={145 4 Pt 1},
  pages={
          872-81
        }
}
Pathophysiologic, morphometric, and biochemical (surfactant and coagulation-fibrinolytic parameters) features were studied in premature baboons with and without bronchopulmonary dysplasia (BPD). A total of 22 baboons were delivered by hysterotomy at 75% of gestation and randomized into two groups. Group 1 (PRN) animals were ventilated with high-frequency oscillation for 48 to 72 h and then changed to positive-pressure ventilation (PPV) while maintained on clinically appropriate oxygen for the… CONTINUE READING
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