Pathology of the inferior olivary nucleus in patients with multiple system atrophy

@article{Sakurai2002PathologyOT,
  title={Pathology of the inferior olivary nucleus in patients with multiple system atrophy},
  author={Atsushi Sakurai and Koichi Okamoto and Masamitsu Yaguchi and Yukio Fujita and Yuji Mizuno and Yoichi Nakazato and Nicholas K. Gonatas},
  journal={Acta Neuropathologica},
  year={2002},
  volume={103},
  pages={550-554}
}
The inferior olivary nucleus (ION) from nine patients with multiple system atrophy was examined with antibodies against α-synuclein, ubiquitin, synaptophysin, glial fibrillary acidic protein, the Golgi apparatus (GA)-trans-Golgi network (TGN), and microglia/macrophages. As previously reported, there were neuronal loss, gliosis, and α-synuclein-positive cytoplasmic inclusions in neurons and glia. In addition, all neurons with α-synuclein-positive cytoplasmic inclusions contained abnormal… CONTINUE READING
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Cellular pathology of the central nervous system

  • GW Kreutzberg, WF Blakemore, MB Graeber
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