Pathology of otosclerosis: a review.

  title={Pathology of otosclerosis: a review.},
  author={Gregory L. Davis},
  journal={American journal of otolaryngology},
  volume={8 5},
Otosclerosis is a bone disorder of unknown etiology confined to the otic capsule. Failure of remodeling of newly formed vascular, woven bone (otospongiosis) results in sclerotic bone (otosclerosis) with abnormal osteons. Involvement of the oval window causes conductive hearing loss. Electron microscopic, histochemical, and biochemical studies identify normal cellular and matrix components of otosclerotic bone without providing clues to the abnormal bone formation and resorption. Plastic… CONTINUE READING