Pathology of nonalcoholic fatty liver disease

  title={Pathology of nonalcoholic fatty liver disease},
  author={Elizabeth M. Brunt},
  journal={Nature Reviews Gastroenterology &Hepatology},
Nonalcoholic fatty liver disease (NAFLD) is a significant complication of obesity and is recognized as the hepatic manifestation of the metabolic syndrome. The process occurs in adults and children and is characterized by the presence of increased amounts of fat in the liver (steatosis). With inflammation, cell death and scarring (fibrosis), the process may result in end-stage liver disease, or be a precursor for hepatocellular carcinoma. Excess hepatic fat is now recognized as an independent… CONTINUE READING
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