Pathology of chronic hepatitis C in children: liver biopsy findings in the Peds-C Trial.

@article{Goodman2008PathologyOC,
  title={Pathology of chronic hepatitis C in children: liver biopsy findings in the Peds-C Trial.},
  author={Zachary D. Goodman and Hala R. Makhlouf and Lea Liu and William F. Balistreri and Regino P. Gonz{\'a}lez-Peralta and Barbara A Haber and Maureen M. Jonas and Parvathi Mohan and Jean Pappas Molleston and Karen F. Murray and Michael R. Narkewicz and Philip John Rosenthal and Lesley J Smith and Patricia R Robuck and Kathleen B. Schwarz},
  journal={Hepatology},
  year={2008},
  volume={47 3},
  pages={836-43}
}
There is relatively little information in the literature on the histopathology of chronic hepatitis C in children. The Peds-C Trial, designed to test the efficacy and safety of peginterferon alfa-2a and ribavirin in children, provided an opportunity to examine liver biopsies from 121 treatment-naïve children, ages 2 to 16 (mean, 9.8 years) infected with the hepatitis C virus (HCV) and with no other identifiable cause for liver disease, signs of hepatic decompensation, or another significant… CONTINUE READING
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