Pathology of aging B6;129 mice.

@article{Haines2001PathologyOA,
  title={Pathology of aging B6;129 mice.},
  author={Diana C. Haines and Santanu Chattopadhyay and Jerrold M Ward},
  journal={Toxicologic pathology},
  year={2001},
  volume={29 6},
  pages={
          653-61
        }
}
Fifty male and 49 female B6;129 mice (wild-type, +/+) were maintained until 2 years of age to study their age-related pathology. By 104-105 weeks, 14/50 (28%) of the males and 30/49 (61%) of the females were still alive. The most common contributing cause of morbidity or mortality was lymphoma. Lymphoma was observed in 21/50 (42%) of the males and 33/49 (67%) of the females with the most common sites being mesenteric lymph nodes, gut associated lymphoid tissue (Peyer's patches), and spleen. The… CONTINUE READING

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