Pathology of Madras type of motor neuron disease (MMND) – a histological and immunohistochemical study

@article{Shankar2000PathologyOM,
  title={Pathology of Madras type of motor neuron disease (MMND) – a histological and immunohistochemical study},
  author={Susarla Krishna Shankar and Mandaville Gourie-Devi and Lavanya Shankar and Thagadur Chickabasavaiah Yasha and Vani Santosh and Sarala Das},
  journal={Acta Neuropathologica},
  year={2000},
  volume={99},
  pages={428-434}
}
A neuropathological report of Madras type of motor neuron disease (MMND) is presented and the differences from other forms of MND are discussed. An 18-year-old girl presented with nerve deafness and slowly progressive bulbo-spinal muscular atrophy, characteristic of MMND. Post-mortem examination of the spinal cord showed a severe loss of anterior horn cells, prominent dilatation of vessels, diffuse, but sparse sprinkling of microglial cells and lymphocytes, and demyelination and sclerosis of… CONTINUE READING

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