Pathology and pathogenesis of idiopathic portal hypertension with an emphasis on the liver.

@article{Nakanuma2001PathologyAP,
  title={Pathology and pathogenesis of idiopathic portal hypertension with an emphasis on the liver.},
  author={Yasuni Nakanuma and Koichi Tsuneyama and Makoto Ohbu and Kazuyoshi Katayanagi},
  journal={Pathology, research and practice},
  year={2001},
  volume={197 2},
  pages={65-76}
}
Idiopathic portal hypertension (IPH) is characterized by a long-standing presinusoidal portal hypertension of unknown etiology in adults. Some unidentified agent(s) affect(s) the intrahepatic small portal veins or portal tracts. Immunological disturbance, thromboembolism, infectious etiology and/or increased fibrogenesis in portal tracts are suspected as being candidates for the primary agent(s). During the long clinical course of IPH, several pathological changes may occur, including… CONTINUE READING

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